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In studies of brain injury models, overexpression of GPX1 can improve spatial learning ability after brain injury in young mice compared with wild-type mice, possibly due to overexpression of GPX1, which reduces oxidative damage in mice at an early stage (Tsuru-Aoyagi et al., 2009)

Consequently, we demonstrate that persister cells acquire a dependency on GPX4

In addition, the AcCoA pool is critical for the synthesis of ergosterol, the key sterol of fungal plasma membranes and a target for two of the three antifungal drugs currently used to treat patients

Oral glutathione at standard doses does not damage healthy kidneys

However, despite their overall safety profile, caution must be used with these medications as several cases have been described in which bronchospasm occurred with their use[71]