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Under-transmission of the variation encoding six alanine residues (ALA6) was observed in the families with autistic disorder, suggesting that this allele may be protective

For example, alpha lipoic acid has shown promise in reducing oxidative stress markers and improving iron levels in -thalassemia major patients ( Other pathways could also be involved in cardiac injury due to iron overload

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The Hippo pathway is mainly composed of the serine/threonine kinase mammalian Ste20-like kinases 1/2, Salvador family WW domain containing protein 1, large tumor suppressor 1/2, MOB kinase activator 1, and transcriptional co-activator YAP 35,36,37,38