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10.1016/j.tox.2014.01.010 44 PizzurroD

Drug and Therapeutics Bulletin

Nature (2013) 504(7480):4515

Furthermore, while vascular normalization has emerged as a promising strategy, biomarkers to predict the response to normalization therapies are still not well-established (100)

This redox balance suppresses NF-B-driven transcription of pro-inflammatory mediators, including COX-2, TLR4 and TLR2 which are currently promoting anti-inflammatory cytokines such as IL-10