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However, long-term use of steroids should be avoided due to potential side effects

Endocr Rev 23 : 824854 Monzavi R and Cohen P (2002) IGFs and IGFBPs: role in health and disease

For cream and lotion formulations, concentrations between 0.05 and 0.2 percent are appropriate, with the peptide pre-dissolved in purified water to ensure even distribution throughout the emulsion system

This makes it especially useful after skin treatments (like micro-needling, laser, microdermabrasion, or peels) or when dealing with flare-ups from rosacea or dermatitis

Researchers suggest that this decline may contribute to the reduced regenerative capacity (such as slower wound healing) of older adults.12 This could mean that, theoretically, adding supplemental GHK to aging skin in the form of products containing GHK-Cu may help it act like younger skin