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Endometriosis: Endometriosis is characterized by the presence of uterine tissue outside the uterus and can cause severe pain

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All these pathologies could theoretically be driven partly or completely by immunogenic self-DNA and in fact, all of them have been related to self-DNA in the context of non-COVID-19 pathologies

Since fermented foods can be used as a probiotic carrier and contain health-promoting components ( Gut Microbiota, Immune System and Rheumatoid Arthritis It is now well established that more than 100 trillion microorganisms, primarily bacteria, colonize the human oral-gastrointestinal tract, most residing in the distal intestine ( The clinical picture of RA results from a complex interaction between various factors, including autoantibodies and signal transduction pathways of the innate and adaptive immune system ( To support the hypothesis that changes in GM composition play a significant role in the onset and progression of RA (Figure 1 summarizes the pathophysiology of RA and the proposed mechanisms whereby GM could participate in triggering autoimmunity and systemic inflammation in susceptible individuals

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