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Use of in vivo expression technology for the identification of putative host adaptation factors of the Lyme disease spirochete

Next, we discuss treatments in development that aim to overcome these barriers, including novel drug designs such as nanoparticles and antibodydrug conjugates, novel methods of drug delivery, including convection-enhanced and intra-arterial delivery, and novel methods to enhance drug penetration, such as bloodbrain barrier disruption by focused ultrasound and laser interstitial thermal therapy

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(2016) investigated the cholesterol-lowering potential of EGCG by administering doses ranging from 107 to 856 mg per day over a period of 4 to 14 weeks