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[2-4] Studies confirm that 97.7% of patients report pain and 68.1% report limited range of motion as primary symptoms (Bass & Poland, 2022)

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Thus, 0.2% (w/w) cuprizone was established to induce highly reproducible and extensive demyelination without detrimental systemic effects in 810 weeks old mice

[DOI] [PubMed] [Google Scholar] Walko TD, Di Caro V, Piganelli J, Billiar TR, Clark RSB, Aneja RK