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doi: 10.1186/s13008-020-00068-z

Studies showed that toxicants trigger the release of excessive inflammatory markers, such as IL-6, Hs-CRP, TNF-, TGF-, and NF-B, and increase liver apoptosis markers, such as Bax, caspase 12, cytochrome c, caspase 9, and caspase 3 [154,165]