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Activated microglia and reactive astrocytes release large amounts of glutamate (Takeuchi et al., 2006

[ 478 ] The increase of oxidative load on cells that are already unhealthy may strikingly counteract the advantages of activating the antioxidant genetic program, rendering it challenging to clearly interpret the posttreatment outcomes

Jiang R, Yamaori S, Okamoto Y, Yamamoto I, Watanabe K

Preparation, characteristics and antioxidant activity of polysaccharides and proteins-capped selenium nanoparticles synthesized by Lactobacillus casei ATCC 393