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8 HuangS.ZhangS.ChenL.PanX.WenZ.ChenY.et al

This compound is found naturally in the skin, connective tissue, joints, and eyes

TNF- induces AQP4 overexpression in astrocytes through the NF-B pathway causing cellular edema and apoptosis

Recognizing the distinction between these forms of fatigue is vital, because untreated fatigue can profoundly affect quality of life, mental health, and the individuals ability to work and engage with society