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Torle J, Dabir PD, Korsgaard U, Christiansen J, Qvist N, El-Hussuna A (2020) Levels of intestinal inflammation and fibrosis in resection specimens after preoperative anti-tumor necrosis factor alpha treatment in patients with Crohns disease: a comparative pilot study

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PMCID: PMC8995671

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Such findings reinforce that urate crystal deposition in tissues can be asymptomatic, but without appropriate management, the process can progress to destructive tophaceous disease ( Figure 1 - 10 ) over varying periods of several years to a decade or more