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498 In macrophages, LXR, which is highly expressed, serves as a crucial link between cholesterol metabolism and inflammatory responses

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This study used 24 male Wistar rats (aged 810 weeks)

Last, to determine the impact of AKT-dependent regulation of glycolysis on NADPH production we used Fluorescence Lifetime Imaging Microscopy (FLIM) technology to compare NADPH/NADH ratio in AKT-E17K and AKT-WT TrC1 in untreated controls and upon irradiation with 5 Gy with and without additional treatment with the AKT-inhibitor MK2206 ( Figure S3E, F )