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Within the framework of recent clinical trial designs, there is no clear clinical evidence that young allogeneic MSCs, despite potentially having better cellular proliferative, senescence, or apoptotic profiles, produce a better biological response in the human OA environment than autologous MSCs

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ICA69 aggravates ferroptosis causing septic cardiac dysfunction via STING trafficking

Interestingly, LILRB2 and KIR3DL2 bind to HLA-B27 dimers with a stronger affinity than HLA-B27, as well as additional conventional HLA-class I heterotrimers, and the binding of KIR3DL2 has been demonstrated to promote the survival and differentiation of inflammatory leukocytes in SpA (40,41)

Cassimatis, M., Orr, R., Fyffe, A., & Browne, G