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This group also demonstrated in human intestinal mucosal Th2-like cell lines from patients with cow milk allergy, that MSSM-002 (50 g/mL) reduced proliferative responses and IL-4, IL-5, and IL-13 secretion, with no effect on IFN- production [95]

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Instead of affecting cortisol, it crosses the blood-brain barrier to bind primarily to Melanocortin receptors (MC4R)

Restoration of astrocytic Hb was accompanied by improvements in hippocampus-dependent memory and normalized synaptic function, as reflected by the spike probability of action potential firing 36 (Fig