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There is a C-to-T single-nucleotide polymorphism at the 718 position (rs713041) located in the 3-untranslated region of the GPX4 gene close to the predicted selenocysteine insertion sequence structure (SECIS, a region of the mRNA required for incorporation of the amino acid Sec into GPX4)

Transplantation 104 , 10191025 (2020)

Plant Physiol Biochem 196:197209 Vilchis-Landeros MM, Vazquez-Meza H, Vazquez-Carrada M, Uribe-Ramirez D, Matuz-Mares D (2024) Antioxidant enzymes and their potential use in breast cancer treatment

[DOI] [PubMed] [Google Scholar] 66.Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, et al

More recent investigations in animal models have focused on the survival and differentiation of implanted cells