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Among these, TGF- signaling is widely recognized as a central mediator of fibrotic progression and has emerged as a key therapeutic target [33, 36]

Firstly, mitochondrial oxidative phosphorylation (OXPHOS) provides the ATP necessary for collagen biosynthesis, post-translational modifications, proteoglycan synthesis, ECM assembly, and fibroblast migration during tissue repair [2,5,12]

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The combination carries low hypoglycaemia risk when used alone, but gastrointestinal side effects (nausea, vomiting, diarrhoea) are common and may be more pronounced initially

It is formulated in the UK and tested for purity and heavy metals at our GMP-certified facility