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[20] These penguins are able to live and thrive in a variety of climates due to their phenotypic plasticity

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The triphenylphosphine analogue metformin (Tpp-Met) leads to phosphorylation of PD-L1 and TGF- by AMPK through inhibition of mitochondrial respiration (OXPHOS), ultimately leading to reduced expression of PD-L1 in the cell membrane and cytoplasm, as well as TGF- (Fig