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In short, giving B12 to special groups needs a careful plan

Antioxidant-rich compounds reduce ROS production, protecting neurons from oxidative stress-induced apoptosis (Simunkova et al., 2019)

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Although these models have yielded invaluable insights into core pathways like pyroptosis and ferroptosis, they fail to fully recapitulate human pathophysiology due to species-specific differences in thermoregulation, inflammatory response kinetics, and hepatocyte metabolism

Iqubal MK, Iqubal A, Imtiyaz K, Rizvi MMA, Gupta MM, Ali J, Baboota S