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doi: 10.1016/j.bcp.2012.03.005

Genetic testing may soon help identify patients who would benefit most from injectable versus oral B6

Pharmacological strategies include metformin to improve IR and correct associated metabolic abnormalities, combined oral contraceptive pills (COCPs) for regulating menstrual cycles and HA, and if needed, anti-androgens for refractory HA ( Resveratrol, a natural polyphenolic compound found in plants such as peanuts, grapes, knotweed, and mulberries ( 2 Resveratrol improves abnormal glucose metabolism IR and compensatory hyperinsulinemia are observed in 65%-95% of women with PCOS, encompassing the majority of overweight/obese individuals and over half of normal-weight women ( Emerging preclinical evidence demonstrates that one-month resveratrol treatment normalizes estrous cyclicity in letrozole-induced PCOS rodent models

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Nuclear receptor Rev-erb: up, down, all around