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The primers for PCSK6 were designed and purchased from Sangon biotech (Shanghai, China): PCSK6 (forward, 5-ACTCCAGAAGAAGAGGAAGAGTA-3

In contrast, various natural and synthetic compounds have been reported to shift Hbs allosteric equilibrium towards a high-affinity state and have also been investigated as potential therapeutic agents for the treatment of sickle cell disease

This mathematical method must meet two assumptions: reaching the maximum response and recording at least two points located near the targeted point of the 50% maximal response

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The question of toxic IgG remains a potentially important but yet unsolved issue, which deserves to be examined in the different PAIS