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Surrounding blood vessels deliver oxygen and nutrients required for rapid cell division, while follicle cells produce the keratin proteins that form the hair shaft

In pathologic conditions, the loss of HS disrupts the charge selectivity of the glomerular filtration barrier, which increases the filtration of proteins and leads to proteinuria (97)

The latter is not yet targeted by approved drugs according to currently available databases and might therefore be interesting for drug repurposing efforts

neoformans infections can also affect the central nervous system and the skin, and in rare cases may become systemic and spread to multiple organs or systems in the body

Interferon- primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway