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added that APOE- 4 is a risk factor, and that patients that are homozygous to this allele will be 8 times more prone to develop AD (Yokoyama et al., 2017)

Briefly, serum samples with a total protein content of 100 g using the Bradford method were loaded on sodium dodecyl sulfate-polyacrylamide gels copolymerized with 0.1% gelatin