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The resulting anaerobic metabolism produces lactic acid and increased acidity (lower pH), which inhibits intramuscular calcium channels, weakening or even stopping contractions

Furthermore, some genes were positively correlated in the three tissues, such as NtGSTU40 , which showed a positive correlation with NtGSTZ1 and NtGSTT2

doi: 10.3390/diagnostics15010021 88 LiSZhugeAChenHHanSShenJWangKet al

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Notably, type 2 diabetes mellitus (T2DM) accounts for more than 90% of all diabetes cases, a statistic that underscores its dominant position in the disease burden