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Inhalation delivery of anticancer agents via HFA-based metered dose inhaler using methotrexate as a model drug

This study is difficult to interpret, however, because only proportion data are provided (no data reflecting magnitude of change are reported) and the study lacks a control for PD natural history

Lo importante es que el porcentaje de pacientes que logr una reduccin mayor de 5% 10% de su peso original aument en 2,5 a 3 veces cuando se adicion orlistat al manejo diettico (16) (Fig

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