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Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina

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However, the ubiquitous presence of antioxidant enzymes that reduce or counteract cellular peroxidation induced by ROS, including glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) (337), glutathione peroxidase (GPX), and peroxiredoxin (Prxs) have been reported in a variety of cells [10,11,12]

Recent intervention strategies targeting metabolic symbiosis nodes, specifically a low-leucine diet combined with YAP inhibitors, can effectively disrupt the TI-Treg OXPHOS-immunosuppression axis by inhibiting the YAP-Lars2-leucine pathway, suggesting novel approaches to overcome tumor microenvironment-mediated immunosuppression and therapeutic resistance

YAP1 and WWTR1 The Hippo pathway is an evolutionarily conserved signaling pathway in control of organ size, tissue homeostasis, and cancer growth