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The study was approved by the hospitals Ethical Committee, and informed consent was obtained from the patients or their family who had agreed to participate in the study

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a g , The representative raw ITC data and the fitted binding curves are shown for the RNA oligonucleotides 5-UUCGUUU C -3 ( a ), 5-UUCGUU C U-3 ( b ), 5-UUCGU C UU-3 ( c ), 5-UUCG C UUU-3 ( d ), 5-UUC A UUUU-3 ( e ), 5-UU U GUUUU-3 ( f ), and as negative control for non-specific RNA 5-CCCCCCCC-3 ( g )