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TNF can directly damage mitochondria in pancreatic acinar cells, leading to ATP depletion and cell death (217)

Mitochondrial dysfunction, a hallmark of AP, contributes to impaired energy metabolism, oxidative stress, and cellular injury, exacerbating disease progression (35)

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A revised ENHANCED track could be implemented in accordance with section 1899(i)(3) of the Act, provided the Secretary determines that such other payment model enhances the quality and efficiency of items and services furnished under the Medicare program and does not result in program expenditures greater than those that would result under the statutory payment model

Multiple studies have shown that FMT is significantly superior to placebo in inducing clinical and endoscopic remission in patients with mild-to-moderate ulcerative colitis (154, 155)