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Cladribine, gemcitabine, lovastatin, and tamoxifen overall have lower IC 50 than the NO-based drugs, which are part of a few cancer and melanoma clinical trials (NCT00060710, NCT05502900) and pronouncedly reduced viability in both, metastatic and therapy-resistant melanoma cell lines (see Supplementary File 1)

Mogazy AM, Hanafy RS (2022) Foliar Spray of Biosynthesized Zinc Oxide Nanoparticles Alleviate Salinity Stress Effect on Vicia faba Plants

En limitant le travail de la tyrosinase, il freine la premire tape de la production de mlanine

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Although numerous previous reviews have explored metabolic reprogramming in cancer, most have predominantly focused on glycolysis or broad metabolic alterations common across multiple tumor types