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Target engagement was confirmed by decreased phospho-tyrosine and NFT burden

doi: 10.1053/j.gastro.2015.02.031

J Clin Oncol 21: 31503157

Higher doses have also been used in studies without any significant side effects

Functionally, these networks can mask polar groups to enhance membrane permeabilityfor instance, the co-assembly of Baicalin (BA) and Berberine (BBR) transforms ionic monomers into amphiphilic nanoparticles, significantly improving transmembrane transport [25]