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Mol Cancer Ther 5:19952006

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A phase I study of indoximod, another IDO inhibitor, in combination with docetaxel, an antimitotic chemotherapy drug, showed stable or partially stable disease conditions in more than 50% of patients [132]

Both insulin and IGF-1 modulate CD4 + T cell metabolism Both insulin and IGF-1 alter the metabolism of metabolic cells and tissues, with insulin particularly well known for increasing glucose uptake 1,9,13

Media was replaced every 2 days and monolayer integrity measured by TEER ( cm 2 , Millicell-ERS Voltohmmeter, Merck Millipore) every 7 days (16 h after media change)