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These measurements allow the calculation of the ratio of GSH/GSSG, or the ratio of reduced to oxidized glutathione, in order to determine the oxidative stress present in cultured mammalian cells in response to a compound

Senescent cells, which were originally thought quiescent, have more recently emerged as an active driver of tissue aging, secreting a number of proteases and cytokines, termed senescence-associated phenotype (SASP), which damage surrounding tissue [47]

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Liu PS, Wang H, Li X, Chao T, Teav T, Christen S, et al