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Heat-sterilized Bifidobacterium breve prevents depression-like behavior and interleukin-1beta expression in mice exposed to chronic social defeat stress

From a proteomic point of view and using a series of multiplexed experiments, Ford et al

Mice treated with the peptide performed much better in a task that required learning to navigate a water maze, which relies on spatial memory, than mice that were treated with a control peptide (a scrambled version of the peptide used to inhibit CDK5-P25)

The cells were stained with DCFH-DA, and the ROS showed green fluorescence under a laser scanning confocal microscope