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Importantly, the biological effects of these compounds appear to be context-dependent, influenced by factors such as dosage, duration of supplementation, exercise modality, and physiological or disease state

Neurology 83 , 10671074 (2014)

Results: In this cohort, median age at initial endoscopic treatment was 67.0 years, and there were 41/66/34 patients with Child-Pugh grade A/B/C, 42 patients were complicated by liver cancer