glutathione and breat cancer cells Catabolism of extracellular supplies cysteine to support tumours Role of Glutathione in Cancer:

Studies reveal that increased polyol pathway flux disrupts glycolysis in diabetic hearts, primarily due to competition between SDH and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for the cytosolic NAD + pool [19]

Biological compounds can be classified into different categories based on their chemical composition, containing polyphenols, terpenoids, alkaloids, flavonoids, etc., all of which have an undeniable ability to induce ferroptosis in tumors

Generation of tolerogenic dendritic cells using lactobacillus rhamnosus and lactobacillus delbrueckii as tolerogenic probiotics

Specifically, it upregulates specific microRNAs (miRNAs) to silence the expression of two critical molecules: miR-155, miR-181b, and miR-361 target Aicda, whereas miR-23b, miR-30a, and miR-125b target Prdm1 (encoding B lymphocyte-induced maturation protein-1, Blimp-1)

These ions subsequently interact with membrane phospholipids and proteins, enhancing permeability and triggering localized membrane disruption and cytoplasmic leakage (Ren et al., 2025)