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However, no significant elevation in TNF- levels was observed in patients with alcohol use disorder (AUD) who exhibited normal serum biochemical profiles [124, 125]

MQ: Methodology, Writing original draft, Investigation

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28

Notably, the endogenous antimicrobial peptide Beta-defensin-2 is upregulated following I/R injury, and moderate suppression of this upregulation may attenuate lung damage by inhibiting excessive inflammation and oxidative stress[92, 93], highlighting its complex role in injury pathogenesis