lactobacillus fermentum me3 glutathione New-generation probiotics - ME-3 Reg'Activ - Immune & Vitality

doi: 10.1017/S0033291700037417 21 EdwardsJCMcGrathSBaldwinALivingstoneMKewleyA

2011;17:500U140

By modifying Au@Pt nanozymes (Bac-Au@Pt) on the bacterial surface, the nano-system can effectively release ROS into tumor cells due to the targeting ability of the bacteria and the catalytic properties of Au@Pt nanozymes under the acidic environment

Similarly, CD73 present in exosomes from endometrial regenerative cells promotes M2 polarization through a MAPK-dependent hydrolysis of ATP, thereby contributing to renal protection (Shao et al., 2025)

Nevertheless, significant challenges persist, including single-target limitations, poor delivery efficiency across the bloodbrain barrier, and insufficient mechanistic insights