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Inflamm Res 68:443458 Korkmaz A, Kolankaya D (2013) Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury

In addition, FTH1 converts Fe 2+ to Fe 3+ , which attenuates lipid peroxidation caused by high levels of free iron and inhibits ferroptosis

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Furthermore, Cu deficiency may lead to reduced NO levels by decreasing SOD1 levels, in turn promoting atherosclerosis via impaired endothelial function, reduced vasodilation, and increased oxidative stress