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SKU: 22545905567
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Antiviral drug discovery and development: challenges and future directions

Ahmed ST, Parkinson R

Gutsche N, Holtmannsptter M, Ma L, ODonoghue M, Busch A, Lauri A, et al

Since cysteine is a precursor of GSH synthesis, maintaining adequate cellular cysteine levels can hinder GSH depletion and enable GPX4 to scavenge lipid peroxidation products continuously (Stockwell et al., 2017)

Expert Opin Pharmacother 12:119130 Knight TR, Kurtz A, Bajt ML, Hinson JA, Jaeschke H (2001) Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress