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That storage is one reason people with a deficiency sometimes feel the benefit for a longer window than someone using shots for simple upkeep

10.1021/acs.langmuir.3c03474 262 ShenL.LeeJ

4,5 Dietary insufficiency, pernicious anemia (i.e., an autoimmune process that reduces available intrinsic factor and subsequent absorption of vitamin B 12 1,2,6,7 ), and long-term use of metformin or acid-suppressing medications have been implicated in B 12 deficiency

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Planning your vial purchases around your current and anticipated dose levels prevents running out