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The drug's mechanismworking centrally rather than peripherallyhas been suggested to potentially offer advantages for men whose ED has a psychological component, but this remains speculative without further research

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10.1016/S0955-2863(99)00033-9 31 MorettiP.PetersS

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Hoang T, Kuljanin M, Smith MD, Jelokhani-Niaraki M

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PMID 24326628

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Furthermore, it regulated the expression of purinergic receptors (including A2A, A3, P2X4, P2X7, and P2Y1), which are recognized for their significant roles in the inflammatory response associated with DED [77]

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