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Studies evaluate downstream effects on insulin receptor signaling, glucose transporter expression, and intracellular pathways involved in metabolic homeostasis

It should be noted that some trials failed to detect any beneficial effects of curcumin, and some trials also failed in elderly subjects and patients with atopic dermatitis, despite the use of significant doses for weeks or months, presumed to be related to bioavailability (Lagoa et al., 2025)

Some other drug options include: Corticosteroids: Local steroid injections can provide pain relief Tumor necrosis factor (TNF) inhibitors: Other biologic treatments: secukinumab (Cosentyx) Oral small molecules: tofacitinib (Xeljanz) AS can affect the whole body, and a person physical therapists eye specialists cardiologists neurologists gastroenterologists A common complication of AS is inflammation of the eyes, causing pain and redness

Biochemical Pharmacology , 178 , 114097

Ferroptosis is a programmed cell death caused by the abnormal increase in iron-dependent lipid peroxidation