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Kang and Bucala, 2019

Similar to our previous study ( 19 ), PHGDH inhibitor suppressed IL-1 secretion while having no effect on TNF- secretion from inflammatory macrophages (Fig

Exogenous ROS burstsoften iron-dependentcan forcibly repolarize TAMs to an anti-tumor M1 phenotype

This approach differs from the use of probability- and nonoptimality-driven heuristic methods traditionally used in bioinformatics and biostatistics

In addition, thyroid hormones affect mitochondrial function, energy expenditure and thermoregulation and are therefore essential for metabolic homeostasis [4]