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In patients with PF, the progression of fibrosis is believed to be influenced by three primary factors: excessive epithelial damage caused by inhaled pollutants, senescence, and genetic susceptibility [32]

Curcumin exerts context-specific autophagy regulation through dual mechanisms: At moderate concentrations (2025 M), it promotes cytoprotective autophagy via inhibition of the mechanistic target of rapamycin (mTOR)-AKT axis (Zhao et al., 2016), evidenced by decreased p-AKT, p-mTOR, and p-P70S6K expression, coupled with increased microtubule-associated protein 1A/1B-light chain 3- II/microtubule-associated protein 1A/1B-light chain 3-I (LC3-II/LC3-I) conversion

Impact of chemical endocrine disruptors and hormone modulators on the endocrine system

Roos I, Sharmin S, Lechner-Scott J et al (2022) Comparison of the effectiveness of ocrelizumab vs interferon , fingolimod and natalizumab on relapses in RRMS

Also, BPC 157 counteracts chronic heart failure (Lovric Bencic et al., 2004) or venous occlusion (Vukojevic et al., 2018)induced hypotension (Lovric Bencic et al., 2004