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10.1016/j.freeradbiomed.2015.04.036 37 DjouadiF.AubeyF.SchlemmerD.BastinJ

For example, Nadatani in 2016 reported that caspase-1 can induce pyroptosis, a unique form of programmed cell death, through the conversion of pro-IL1 and pro-IL18 in their active forms, which promotes further inflammation

Ferroptosis in degenerative diseases is unlikely to be driven by a single event such as iron excess

Similarly, the activity of the selenium-containing glutathione peroxidase enzyme, responsible for speeding up the reaction between glutathione and free radicals (such as hydrogen peroxide) will be negatively affected if dietary selenium is low and enhanced when selenium is high

Likewise, phylogenetic tree highlights a similarity between GSTe4 sequences from Benin, Cameroon, and Uganda compared to Malawi GSTe4 sequences which are highly polymorphic and form a separate clade (Fig