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A common theme among all current clinically used ADT approaches is that, despite an initial remission, resistance invariably develops over time [4]

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J Biol Chem 276:1577615782

In the same study, the human colon carcinoma cell line HCT116 was revealed to be less sensitive to the bleomycin treatment, in line with the very low expression of CT2 and with the metabolism based on glycolysis rather than on FAO (Table 1)