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Moreover, mutant KRAS CRC cells were more dependent on the glutaminolysis pathway for energy supply than were wt KRAS CRC cells [52]

Results PCR verification of GDH2 / GDH3 genes knockout mutagenesis The SAT1 flipper disruption cassettes for GDH2 and GDH3 gene deletions were generated successfully by PCR

Though ALA treatment led to lower levels of lipid peroxidation and higher antioxidants in the intervention study, these changes did not fully prevent glaucoma-related declines in RGC number and function