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Furthermore, through epigenetic mechanismsspecifically the acetylation of histonesALCAR can upregulate specific receptors like metabotropic glutamate 2 (mGlu2), a pathway that stimulates neurogenesis, enhances synaptic plasticity, and has been strongly tied to the compound's clinical antidepressant effects

evaluated the effectiveness of combining physical rehabilitation with ALCAR therapy in patients suffering from Post-COVID syndrome

A meta-analysis of 43 trials revealed that carnitine supplementation in doses ranging from 500 mg to two grams daily anywhere between two and 54 weeks significantly decreased body weight and fat mass (7)

It is also crucial to note that patients should strictly avoid any supplements containing D-carnitine or DL-carnitine

The data revealed that carnitine supplementation exhibited significant positive clinical effects in nearly 42% of patients, specifically targeting the profound cellular energy deficits that make upright posture intolerable