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Costunolide ameliorates MNNG-induced chronic atrophic gastritis through inhibiting oxidative stress and DNA damage via activation of Nrf2

Numerous studies have demonstrated its effectiveness in stimulating fibroblasts, the cells responsible for collagen synthesis

The hallmark of the PPHN pathophysiology is increased pulmonary vascular resistance (PVR) resulting in decreased pulmonary blood flow (PBF) and hence, decreased amount of oxygenated blood returning to left side of the heart leading to hypoxia, decreased end-organ perfusion, acidosis and cyanosis (9)

Viscosity was evaluated over a shear rate range of 0.110 0 s 1 under controlled- shear conditions

[DOI] [PubMed] [Google Scholar] 84.Sonboli A., Babakhani B., Mehrabian A.R