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It was shown to inhibit cytochrome c oxidase, leading to cell death through ATP depletion (Figure 1)

If researchers determine that there are specific and consistent differences in the gut, bacteria may serve as biomarkers objective measurements to diagnose or track PD

Experimental findings further revealed that increased expression of fructose-metabolizing enzymes and fructose exposure in cardiomyocytes promoted glycolytic activity and lipid accumulation, strongly suggesting a direct role of the polyol pathway in diabetic cardiac dysfunction [24]

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In agreement, the early expression of SAG13 and SAG15 was also evident in vtc1 mutants (Barth et al., 2013b)