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Public Health 97 , 362368 (2006)

GenBank AA309096 EST179872 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end, mRNA sequence

The small-molecule inhibitor selectivity between IKKalpha and IKKbeta kinases in NF-kappaB signaling pathway

This study documented in humans the variability of the leak pathway in response to systemic inflammation versus the constancy of the pore pathway, and that very large solutes cannot penetrate the paracellular barrier, even in the presence of inflammation